submitted with permission by Marj Brooks
with thanks to Kevin & Donna Frizzell of DeSaix St. Bernards for generously allowing us to use many of their superb array of articles
DRUGS CONTRAINDICATED IN PREGNANCY
| Drug |
Adverse Effects |
| Acetazolamide |
Foetal Anomalies |
| Amphotericin B |
Congenital Anomalies |
| Androgens |
Masculinization of Fetus |
| Antineoplastics |
Fetal Death or Anomalies |
| Bishydroxycoumarin |
Fetal Death & Intrauterine Haemorrhage |
| Chloramphenicol |
Foetal Death |
| Chlorpromazine |
Neonatal Hepatic Necrosis |
| Cholinesterase Inhibitors |
Neonatal Myasthenis |
| Corticosteroids |
Cleft Palate |
| Diazoxide |
Destruction of Foetal Islet Cells |
| Dimethylsulfoxide |
Congenital Anomalies |
| EDTA |
Congenital Anomalies |
| Estrogens |
Feminization of Foetus |
| Ethoxyzolamide |
Congenital Anomalies |
| Fluocytosine |
Congenital Anomalies |
| Griseofulvin |
Congenital Anomalies |
| Gold Salts |
Congenital Anomalies |
| Indomethacin |
Premature Closure of Ductus Arteriosus |
| lododeoxyuridine |
Congenital Anomalies |
| Iodides |
Fetal Goiter |
| Iodinated Casein |
Neonatal Goiter |
| Isoniazid |
Retarded Psychomotor Activity |
| Isoproterenol |
Fetal Tachycardia |
| Lithium salts |
Fetal Goiter |
| Meclizine |
Congenital Anomalies |
| Meperidine |
Inhibit Closure of Ductus Arteriosus |
| Mepivacaine |
Fetal Bradycardia |
| Methoxamine |
Placental Vasoconstriction & Foetal Hypoxia |
| Nitrofurantoin |
Fetal Haemolysis |
| Paracetamol |
Methemoglobinaemia |
| Phenylbutazone |
Neonatal Goiter & Nephrosis |
| Phenylphrine |
Placental Vasoconstriction - Foetal Hypoxia |
| Prochlorperazine |
Congenital Anomalies |
| Propranolol |
Foetal Bradycardia |
| Propylthiouracil |
Neonatal Goiter |
| Quinine |
Deafness and Thrombocytopenia |
| Reserpine |
Respiratory Obstruction |
| Salicylates |
Neonatal Bleeding |
| Sodium Selenites |
Impaired Growth of Foetus |
| Streptomycin |
Hearing Loss & Congenital Anomalies |
| S.R. Sulfonamides |
Liver Atrophy and Hyperbilirubinemia |
| Tetracyclines |
Impaired Bone and Tooth Development |
| Thiazides |
Foetal Death and Thrombocytopenia |
| Vitamin A |
Multiple Anomalies |
| Vitamin D |
Hypercalcemia & Mental Retardation |
| Vitamin K Analogs |
Hyperbilirubinemia |
| Warfarin |
Intrauterine Haemorrhage |
DRUGS CONSIDERED TO BE SAFE DURING PREGNANCY
| Acetylcysteine |
Disophenol |
Morphine |
| Ammonium Chloride |
Doxapram |
Neomycin |
| Amoxicillin |
Doxylamine |
Niclosamide |
| Ampicillin |
Enflurane |
Nitrous Oxide |
| Atropine |
Ephedrine |
Oxytocin |
| Cephalexin |
Erythromycin |
Penicillin |
| Cephaloridine |
Ethrane |
Pentobarbital |
| Cephalothin |
Furosemide |
Phenobarbital |
| Chloramphenicol |
Gentamicin |
Pilocarpine |
| Chlorpheniramine |
Glycopyrrolate |
Piperazine |
| Chymotrypsin |
Guaifenesin |
Polymyxin B |
| Clindamycin |
Halothane |
Pralidoxime |
| Clonazepam |
Heparin |
Primidone |
| Codeine |
Kanamycin |
Procaine |
| Colistin |
Ketamine |
Pyrantel |
| Dextromethorphan |
Lidocaine |
Pyrilamine |
| Diazepam |
Lincomycin |
Salbutamol |
| Dichlorvos |
Mannitol |
Spironolactone |
| Dicloxacillin |
Mebendazole |
Sulfonamides |
| Diethylcarbamazine |
Metaproterenol |
Tetracaine |
| Diethyl Ether |
Methapyrilene |
Theophylline |
| Digitoxin |
Methenamine |
Thiopental |
| Digoxin |
Methohexital |
Tiletamine |
| Dimenhydrinate |
Metronidazole |
Triamterene |
| Diphenhydramine |
Miconazole |
Urokinase |
DRUGS NOT PROVEN TO BE SAFE FOR USE DURING
PREGNANCY BUT NOT NECESSARILY CONTRAINDICATED
| Acepromazine |
Glycobiarsol |
Procainamide |
| Aminopentamide |
Hexylcaine |
Prochlorperazine |
| Aminopromazine |
Hydralazine |
Promazine |
| Arsenamide |
Hydrocortisone |
Proparacaine |
| Aspirin |
Iron Dextran |
Propiopromazine |
| Bithionol |
Lenperone |
Pyrimethamine |
| Bunamidine |
Levamisole |
Quinacrine |
| Butorphanol |
Liothyronine |
Quinidine |
| N-Butyl Chloride |
Meprobamate |
Ronnel |
| Caffeine |
Methocarbamol |
Saffan |
| Chlorpromazine |
Methoxyflurane |
Spectinomycin |
| Chlorprothixene |
Methylprednisolone |
Stanozolol |
| Cimetidine |
Neostigmine |
Styrylpyridium |
| Colchicine |
Nitroglycerine |
Thiabendazole |
| Cortisone |
Nitroprusside |
Thyroxine |
| Cythioate |
Nystatin |
Toluene |
| Dapsone |
Phenoxybenzamin |
Trichlorfon |
| Dichlorophene| |
Phthalofyne |
Trifluomeprazine |
| Dithiazanine |
Physostigmine |
Trimethoprim |
| Dobutamine |
Prazosin |
Xylazine |